Limit of 4 per person on Levafas Diamond 1ltr & 4ltr sizes. Orders exceeding this quantity will be cancelled

Levafas Diamond fluke and worm drench for sheep and cattle is a broad spectrum anthelmintic that is used as an oral drench in the treatment and control of gastro-intestinal and pulmonary roundworm infections and adult liver fluke infections. The active ingredient in Levafas Diamond is Levamisole hydrochloride. Levamisole is highly effective in the treatment of mature and developing immature stages of a wide range of important roundworm species in sheep and cattle.

Active Ingredient: Levamisole hyrochloride, Oxyclozanide

Target Species: Cattle, sheep

Treats and Controls: Liver fluke, roundworms

Administration Method: Oral drench

Withdrawal Time: 28 days for cattle intended for meat and offal, not permitted for use on cattle producing milk for human consumption. 10 days for sheep intended for meat and offal, not permitted for use on sheep producing milk for human consumption.

Dosage for cattle: 12.5 ml per 50 kg of bodyweight

Dosage for sheep: 2.5ml per 10kg Bodyweight

Always read the label and all enclosed information for Levafas Diamond before administering to animals!

What is the financial cost of fluke infections?

According to "Liver Fluke - the Facts", a paper published by Animal Health Ireland (AHI), liver fluke costs the worldwide livestock and food industries an estimated €2.5 million per year. These financial losses associated with liver fluke are mainly due to a reduction in the amount of milk and meat produced. Liver fluke can cause a loss of up to 20% in cattle, 30% in sheep and a loss of up to 8% in the milk production of dairy cows.

Animals become infected with liver fluke by ingesting encapsulated Larvae (metacercariae). These larvae are picked up when the animal grazes on contaminated grass. It is very common that farms have a wet and "flukey" area that shouldn't be used for grazing at times of year when the metacercariae are present. Nonetheless, cattle and sheep still graze on these areas so we must accept that liver fluke is still a problem in the livestock industry.

What are the signs and effects of livestock infected with other parasites?

Features of Levafas Diamond 

• Fluke and worm drench for sheep and cattle
• A broad spectrum anthelmintic that is used as an oral drench
• Treats and controls of gastro-intestinal and pulmonary roundworm infections and adult liver fluke infections.
• Active ingredient is Levamisole hydrochloride.
• Highly effective in the treatment of mature and developing immature roundworm species in sheep and cattle.

​This product is only licensed for sale within the Republic of Ireland

Click here to Download Data Sheet

Health Products Regulatory Authority 

Summary of Product Characteristics

1 NAME OF THE VETERINARY MEDICINAL PRODUCT
Levafas Diamond Fluke and Worm Drench

2 QUALITATIVE AND QUANTITATIVE COMPOSITION
Active Substances
Levamisole hydrochloride 3.0 % w/v
Oxyclozanide 6.0 % w/v

Excipients
Sodium metabisulphite (E223) 0.15 % w/v
Tartrazine (E102) 0.011 % w/v
Sodium methyl parahydroxybenzoate (E219) 0.18 % w/v

3 PHARMACEUTICAL FORM
Oral suspension.
A yellow viscous suspension.

4 CLINICAL PARTICULARS
4.1 Target Species
Cattle, sheep.

Active Substances
Levamisole hydrochloride 3.0 % w/v
Oxyclozanide 6.0 % w/v

Excipients
Sodium metabisulphite (E223) 0.15 % w/v
Tartrazine (E102) 0.011 % w/v
Sodium methyl parahydroxybenzoate (E219) 0.18 % w/v

4.2 Indications for use, specifying the target species
For the treatment and control of both gastro-intestinal and pulmonary nematode infections and adult liver fluke
infections in cattle and sheep.
Levafas Diamond Fluke and Worm Drench should be used in cases of parasitic gastroenteritis and lungworm caused by those organisms sensitive to treatment with Levamisole hydrochloride.
Levamisole is effective against mature and developing immature stages of a wide range of important nematode species and is highly effective against the following:

Lungworms:
Dictyocaulus spp.

Gastrointestinal worms:
Trichostrongyles spp.
Cooperia spp.
Ostertagia spp. (except inhibited Ostertagia larvae)
Haemonchus spp.
Nematodirus spp.
Bunostomum spp.
Oesophagostomum spp.
Chabertia spp.

Levafas Diamond Fluke & Worm Drench also removes most mature Fasciola spp. (flukes) present in the bile ducts of
the liver.

4.3 Contraindications
Do not use in animals known to be hypersensitive to the active substances

4.4 Special warnings for each target species
Care should be taken when treating heavily pregnant animals or animals under stress from adverse weather conditions, poor nutrition, penning, handling, etc..
Levafas Diamond Fluke and Worm Drench is not effective against Type II Ostertagiasis (winter scours) in cattle.
In cases of lungworm infections, coughing may persist for a considerable time following successful treatment with Levafas Diamond Fluke and Worm Drench.
This is due to tissue damage caused by the parasites.
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
- Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
- Underdosing which may be due to underestimation of bodyweight, misadministration of the product, or lack of
calibration of the dosing device.
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the tests strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.

4.5 Special precautions for use

Special precautions for use in animals
When using a dosing gun to administer this product, care must be taken to avoid dosing gun pharyngitis.
After treatment, animals should be moved to clean pasture in order to prevent re-infection.
Where this is not done, further dosing at 10-14 day intervals may be necessary.

Special precautions to be taken by the person administering the veterinary medicinal product to animals
When using, do not eat, drink or smoke.
Wash splashes from eyes and skin immediately.
Take off immediately any contaminated clothing.
Wash hands and exposed skin before meals and after work.
Levamisole can cause idiosyncratic reactions and serious blood disorders in a very small number of people.
If symptoms such as dizziness, nausea, vomiting or abdominal discomfort are experienced when using the product, or sore mouth/throat or fever occur shortly afterwards, then medical advice should be sought immediately.

4.6 Adverse reactions (frequency and seriousness)
At normal oxyclozanide dose levels, cattle may show slight softening of the faeces with the occasional animal showing increased frequency of defecation and transient inappetance.

4.7 Use during pregnancy, lactation or lay
The product can be safely administered to pregnant or lactating animals.

4.8 Interaction with other medicinal products and other forms of interaction
Concurrent treatment with products containing organophosphorus compounds or diethylcarbamazine citrate should be avoided.
These compounds should not be administered within a period of 14 days before or after treatment with Levafas Diamond Fluke and Worm Drench.

4.9 Amounts to be administered and administration route
To ensure administration of a correct dose, bodyweight should be determined as accurately as possible; accuracy of the dosing device should be checked.
If animals are to be treated collectively rather than individually, they should be grouped according to their bodyweight and dosed accordingly, in order to avoid under- or overdosing. Levafas Diamond Fluke and Worm Drench should be administered as an oral drench.

Dosing may be carried out using a drenching bottle or a suitable gun system, at a rate of 7.5 mg levamisole
hydrochloride/kg bodyweight and 15 mg oxyclozanide/kg bodyweight achieved by administering
25 ml per 100 kg bodyweight in cattle and
2.5 ml per 10 kg bodyweight in sheep.

The veterinary surgeon should give advice regarding appropriate dosing programmes and stock management to achieve adequate parasite control.

4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
If recommended dosages are exceeded animals may exhibit signs of overdosage.
The effects of levamisole overdosage include impaired motor function i.e. muscle tremors, head shaking and increased salivation. These effects are transient and more likely to be found in cattle than in sheep.
The effects of oxyclozanide overdosage are dullness and some loosening of faeces in sheep and possible diarrhoea, inappetence and loss of weight in cattle.
The effects are occasionally enhanced in animals with severe liver damage and/or dehydration at the time of dosing.

4.11Withdrawal Period(s)

Animals must not be slaughtered for human consumption during treatment.
Cattle may be slaughtered for human consumption only after 28 days from the last treatment.
Sheep may be slaughtered for human consumption only after 10 days from the last treatment.
Do not use in animals producing milk for human consumption.

5 PHARMACOLOGICAL or IMMUNOLOGICAL PROPERTIES
Pharmacotherapeutic group:
Anthelmintics, levamisole, combinations

ATCvet code:
QP52AE51

5.1 Pharmacodynamic properties
Levamisole is an imidazothiazole that acts by interfering with parasite nerve transmission causing muscular paralysis.
It is effective against adult and immature gastro-intestinal roundworm and lungworm infections.
Oxyclozanide is a salicylanilide which is mainly active against adult liver flukes. It is distributed to the liver, kidney and intestines and is excreted in the bile.

6 PHARMACEUTICAL PARTICULARS
6.1 List of excipients
Sodium citrate
Anhydrous citric acid
Sodium metabisulphite (E223)
Disodium edetate
Polysorbate 80
Xanthan gum
Tartrazine (E102)
Sodium methyl parahydroxybenzoate (E219)
Antifoam M30
Purified water

6.2 Incompatibilities
None known.

6.3 Shelf-life
Shelf-life of the veterinary medicinal product as packaged for sale: 2 years.

6.4 Special precautions for storage
Do not store above 25°C.
Protect from light.

6.5 Nature and composition of immediate packaging
Low density polyethylene containers of 1 litre, 2.5 litres, 4 litres and 10 litres.
Not all pack sizes may be marketed.

6.6 Special precautions for the disposal of unused veterinary medicinal products or waste materials
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.

7 MARKETING AUTHORISATION HOLDER
Norbrook Laboratories Limited
Station Works
Newry, 
Co. Down
Northern Ireland
BT35 6JP

8 MARKETING AUTHORISATION NUMBER(S)
VPA 10999/036/001

9 DATE OF THE FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION
30th September 2009

Drench correctly
Sheep Oral Drench
The drenching technique is a vital part of ensuring that the wormer does its job effectively.
Make sure the sheep are properly restrained and cannot leap around when they are being drenched so they swallow the whole amount.
Sheep can also suffer serious injury, or even death, if they are unrestrained and the gun penetrates the tissues at the back of the mouth.
Place a hand under the head and tilt slightly to the side.
Slot the nozzle in the gap between molar and incisor teeth and then over the back of the tongue.
If the wormer is just put into the mouth, it will bypass the rumen as it escapes down the oesophageal groove and will be less effective.
This is particularly important for white (BZ) drenches.

Dosing Weight – do not guess. Underestimating the weight of an animal is a common cause of underdosing.
Select and weigh the biggest animal in the group to determine the correct dose.
If there is a wide range of weights, consider splitting the group, then weigh the heaviest in each section.
Do not forget to check that the weigh crate is accurate before starting!

Calibrate and maintain the drench gun
Always check the gun is delivering the right amount before you drench.
Remove the plunger from a 10 ml syringe, put a thumb over the end and squirt the dose into it, making sure there are no air bubbles left.
Adjust the gun until the dose delivered is correct.
Drenching guns should also be well maintained and replaced regularly.
Clean with warm soapy water after use and check springs and tubes to make sure there are no kinks that will form air bubbles.

Withholding food
Research has shown that the efficacy of the white (BZ) and clear (AV) drenches can be improved by withholding food for 12–24 hours before treatment.
It is not advised to deprive heavily pregnant ewes of food, so if you treat this class of stock with anthelmintics, you may wish to use yellow drenches (LV) because their efficacy is less dependent on rumen fill.

Storage
Wormers should be stored securely, away from direct sunlight at 4–25°C.
Check the use-by date and, once open, use within the time shown on the packaging.
Shake white (BZ) products well before use.

 Cattle Oral drenches
Oral drenching guns are designed to deliver the treatment towards the back of the mouth over the tongue, so the entire dose is swallowed at once to optimise efficacy.
• Make sure animals are properly restrained, with their head held up
• Slide the nozzle of the dosing gun in the side of the mouth and over the tongue so that the entire dose is swallowed immediately
• Drenching equipment must be correctly calibrated and in good working order
• Calibrate the gun using the product just before treatment starts by delivering two or more doses into a graduated measuring cylinder.
Faulty equipment, or attempting to dose too quickly, may mean that the barrel of the gun does not fill properly or that the liquid is full of bubbles.

Delivery Information

Delivery Service

Here at Agridirect we have joined forces with DPD to ensure all packages are delivered promptly and safely to you. We ship to all mainland countries within the EU. Deliveries take place Monday to Friday excluding bank holidays. Once your order has been dispatched from our warehouse you will be notified by email. If there is a delay with your order for any reason you will be contacted immediately. 

Due to Brexit we are temporarily unable to ship to the UK. Shipping to Northern Ireland will remain in place.

Delivery Times

Some products have an extended delivery time, this is noted on the products.

Delivery Rates

A selection of the products we sell are only licensed for sale within the Republic Of Ireland and can not be shipped outside of the country. These products are noted as only being available within the Republic of Ireland on the individual product pages.

There may be an addition charge on certain bulky items. This charge will be clearly marked on an applicable products and will be explained on the checkout page before payment has been made.

Agridirect Returns Policy

We’re sorry your purchase didn’t work out. But don’t worry; we have a great returns policy to help you out.

All purchases can be returned to us within 14 days of delivery and returned goods must be received within 14 days from the date you informed us of the return.

Purchases may be opened for inspection but must not be used and must be repackaged securely in the original packaging if you wish to return it.

If we discover goods have been used or there has been a loss in value of the goods due to damage to the goods, while in your care or whilst being returned to us, we will reduce the amount refunded, which may amount to the full cost of the product, to cover loss of value of goods.

All returns should be complete which includes boxes, manuals and accessories that may have been included with the order.

All returns must be packaged appropriately for shipping, we will not accept responsibility for damages or loss which occur during shipping of a return product.

We accept no responsibility for goods damaged or lost while in transit to us. 

How do I return a product?

We have partnered with DPD to make your returns process easy and secure. simply follow the steps below and bring your package to an official DPD pickup point.

1) All returns must be accompanied with a fully filled out returns form which can be downloaded here.

2) To print off your return label click here or visit www.dpd.ie/returns and follow the on-screen instructions. Make sure and use your order number as your reference.

• Select “Continue as Guest”
• Select “Agridirect” from the drop-down menu
• Select your reason for returning
• Select the size of the package you wish to return
• Accept DPD’s terms and conditions
• Fill in your payment details
• Fill in your own details
• Follow the instructions to print off your label

3) Bring your package to a DPD pickup point. To find your nearest drop off point here.

Once the returned product has been received into our warehouse and been fully inspected a refund will be issued.

If you choose not to use the DPD returns service we recommend that you use a method that can be tracked.

For the return of bulk products please contact us at sales@agridirect.ie

I have received a damaged product from you, what should I do?

First off, if you have received a damaged electrical product from us, do not plug it in. Any electrical products that are plugged in are deemed ‘as used and accepted’ and are not accepted as returns. All damages must be reported to us via phone or email within 24hours of receipt of goods. Please ensure you check your items upon delivery.

How do I begin the returns process?

If you wish to begin the return process, please email us at sales@agridirect.ie and ensure the following information is included in your email. Your name, phone number, Order id, the item you wish to return, reason for return and if the product is damaged we require photos of the product.

Once you have sent us all required information a member of our team will assess your claim and will contact you as soon as possible. Please hold off on returning products until a member of our team has called you to confirm.

Refunds

Once the returned product has been returned to us and fully inspected a refund will be issued.

Please Note: A typical timeline for a refund to show in your account is up to 10 working days from the date processed, depending on your bank.