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Abacare Pour-on (Abamectin)
Abacare Pour-on (Abamectin)

Abacare Pour-on (Abamectin)

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Abacare is a broad spectrum, long acting, low dosage rain resistant pour on used for the treatment and control of internal and external parasites in cattle.

Abacare is an easy to use antiparasitic used for the treatment and control of roundworms, lungworms, sucking and biting lice.
The active ingredient in 
Abacare is abamectin which is highly effective against internal and external parasites. 
 

Active Ingredient:
Abamectin

Target Species:
Cattle

Administration Method: 
Pour-on

Treats and Controls: 
Roundworms, lungworms, sucking and biting lice

Withdrawal Time: 
35 days for animals intended for meat and offal, not permitted for use on animals producing milk for human consumption.

Dosage: 
1 ml per 20 kg of bodyweight

Body Weight Dose Volume Number of full doses per pack:
2.5 Litre
50kg 2.5 ml 1000
100kg 5 ml 500
150kg 7.5 ml 333
200kg 10 ml 250
250kg 12.5 ml 200
300kg 15 ml 167
350kg 17.5 ml 143
400kg 20 ml 125
450kg 22.5 ml 111
500kg 25 ml 100
550kg 27.5 ml 91
600kg 30 ml 83

Always read the label and all enclosed information for Abacare Pour-on before administering to animals!

Key Features of Abacare

  • Is broad spectrum
  • Long acting,
  • Low dosage
  • Rain resistant  
  • Abacare is easy to use  
  • Used for the treatment and control of roundworms, lungworms, sucking and biting lice.
  •  Highly effective against internal and external parasites.

The Effects Of Parasites In Cattle

Lungworm:
 
Symptoms: Short, sharp cough that becomes worse with exercise, in severe cases the animal will have obvious difficulty breathing.
 
Effects: Lungworm infections cause a high susceptibility to respiratory viruses and bacteria. Infected cattle are prone to contracting severe bronchial pneumonia which if left untreated can lead to death.
Roundworm:
 
Symptoms: Lack of thrive, watery scour, loss of weight
 
Effects: Roundworms can puncture the blood vessels of a cow to feed on their blood. This can lead to anemia, poor growth, malnutrition and if left untreated can cause death.
Lice:
 
Symptoms: Scratching, biting, greasy appearence, missing clumps of hair
 
Effects: Severe infections can cause pneumonia and anemia and can even lead to death.
 

 

​This product is only licensed for sale within the Republic of Ireland

Click here to Download Data Sheet

Health Products Regulatory Authority

 Summary of Product Characteristics

1 NAME OF THE VETERINARY MEDICINAL PRODUCT
Abacare 1% w/v Pour-On Solution

2 QUALITATIVE AND QUANTITATIVE COMPOSITION

Active:
Abamectin 1% w/v

Excipients:
Benzyl Alcohol 25% w/v (as preservative)
For a full list of excipients, see Section 6.1.

3 PHARMACEUTICAL FORM
Pour-on Solution.
A clear straw coloured oily solution.

4 CLINICAL PARTICULARS

4.1 Target Species Cattle/Beef and non-lactating dairy cattle.

4.2 Indications for use, specifying the target species
A broad-spectrum endectocide of the avermectin family, effective against internal and external parasites sensitive to the family.
For the treatment and control of the following mature and immature roundworms in cattle: Haemonchus spp, Ostertagia spp, Cooperia spp, Trichostrongylus spp, Oesophagostomum spp, Nematodirus spp, Trichuris adults and Dictyocaulus spp.
Also for the treatment and control of sucking and biting lice (Linognathus vituli and Damalinia bovis, respectively).

4.3 Contraindications
Do not concurrently treat animal with drugs which can increase GABA activity, such as barbital. Do not use in known cases of hypersensitivity to the active ingredient. Do not use in other species.

4.4 Special warnings for each target species
None.

4.5 Special precautions for use Special precautions for use in animals
Assess body weight as accurately as possible before calculating dosage.
Intensive use or misuse of anthelmintics may give rise to drug resistance.
To reduce this risk, dosing programs should be discussed with your veterinary surgeon.

Special Precautions to be taken by the Person Administering the Product to Animals
Avoid contact with the skin.
Do not smoke or eat while handling the product.
The use of plastic gloves is advised.
Wash hands after use.
If the drug is taken by mistake immediately seek medical treatment.
Emetine or Ephredine may be useful.

4.6 Adverse reactions (frequency and seriousness)
None.

4.7 Use during pregnancy, lactation or lay
Do not use in cattle producing milk for human consumption.

4.8 Interaction with other medicinal products and other forms of interactions
None known.

4.9 Amounts to be administered and administration route
Abacare Pour-on is ready to use through standard pour-on equipment. It is Good Veterinary/Farming Practice to calibrate administration equipment.
Cattle: 1ml /20 kg body weight (based on recommended dose of 500 micrograms of Abamectin per kg body weight) poured on the mid-back of the animal if using the pump pack or using a pour-on gun attached to the specially made container cap.

4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
Trials showed that a dose of 1000 microgram / kg, single or repeated after 21 days, caused no adverse drug reactions. However several fold overdose of the injectable formulation can cause toxicity; animals will become recumbent within 24 hours and may not recover, there is no antidote.

4.11 Withdrawal period(s)
Cattle must not be treated within 35 days of slaughter for human consumption.
Do not use in cows producing milk for human consumption.
Do not use in non-lactating dairy cows, including pregnant heifers within 60 days of calving.

5 PHARMACOLOGICAL or IMMUNOLOGICAL PROPERTIES
Abamectin or Avermectin B1 is the natural fermentation product from Streptomyces avermitilis containing not less than 90% of the B1a component and not more than 10% of the B1b component.

ATC Vetcode:
QP54AA02

5.1 Pharmacodynamic properties
The action of the avermectins is on nematode and arthropod parasites by paralysing them through potentiating the presynaptic release of gamma amino butyric acid (GABA).

5.2 Pharmacokinetic particulars
The pharmacokinetic profile of avermectins may be influenced by the formulation used.
Abacare Pour-on is formulated in a carrier vegetable oil base. Vegetable oils are preferred to effectively cause permeation through the skin. The persistent (35 days) blood levels of Abamectin reflected this.
Avermectins are widely dispersed in all tissues with the liver and fat levels being the highest.
Excretion is mainly intra intestinal, through bile, and the drug is eliminated via the faeces.

6 PHARMACEUTICAL PARTICULARS

6.1 List of excipients

Benzyl Alcohol
Soya Bean Oil

6.2 Major incompatibilities
None known.

6.3 Shelf-life
Shelf life of the veterinary medicinal product as packaged for sale: 18 months.

6.4 Special precautions for storage
Do not store above 25°C.
Protect from light.
Store in tightly closed original container in the upright position.

6.5 Nature and composition of immediate packaging
1 L and 2.5 L back pack flat bottomed HDPE containers provided with a cap on which normal pour-on equipment can be fitted. Not all pack sizes may be marketed.

6.6 Special precautions for the disposal of unused veterinary medicinal products or waste materials derived from the use of such products
ABAMECTIN IS EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE.
Do not contaminate surface waters or ditches with the product or used containers.
Unused product or waste material should be disposed of in accordance with current practice for pharmaceutical waste under national waste disposal regulations.

7 MARKETING AUTHORISATION HOLDER
J. & M. Veterinary Services Ltd
30 Coolmine Business Park,
Clonsilla Road,
Dublin 15
Ireland
8 MARKETING AUTHORISATION NUMBER(S)
VPA10954/010/001

9 DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION
Date of first authorisation: 23 February 2001
Date of last renewal: 22 February 2006

10 DATE OF REVISION OF THE TEXT
March 2021

Cattle Pour-ons

These should be applied along the length of the flattest part of the animal’s back, from the withers to the tail head.
In general, animals should not be treated when the hair is wet or if rain is anticipated within two hours of treatment. However, some products are waterproof and can be used on wet animals.
Areas of damaged skin should be avoided, as should areas contaminated with mud or manure

 

What is Abamectin

Abamectin
 is a widely used insecticide and anthelmintic.
Abamectin, is a member of the Avermectin family and is a natural fermentation product of soil dwelling actinomycete Streptomyces avermitilis
Abamectin (also called Avermectin B1), differs from Ivermectin, the popular member of the Avermectin family, by double bond on C-22-25. 
Fermentation of Streptomyces avermitilis yields 8 closely related Avermectin homologues out of which B1 (a and b) forms the bulk of the fermentation. 
The non-proprietary name, abamectin, is a combination of Bla (~ 80%) and B1b (~ 20%). 
Out of all the Avermectins, abamectin is the only one that is used both in agriculture and pharmaceuticals.

How does Abamectin work?

Avermectins bind to the glutamate-gated chloride channels that are found in invertebrate nerve and muscle cells. 
They cause hyperpolarization of these cells resulting in paralysis and death. 
Mammals only possess glutamate-gated chloride channels in the brain and spinal cord and as the Avermectins have a low affinity for other mammalian ligand-gated channels and do not usually cross the blood–brain barrier, they are very safe for mammals.

Delivery Information

Delivery Service

Here at Agridirect we have joined forces with DPD to ensure all packages are delivered promptly and safely to you. We ship to all mainland countries within the EU. Deliveries take place Monday to Friday excluding bank holidays. Once your order has been dispatched from our warehouse you will be notified by email. If there is a delay with your order for any reason you will be contacted immediately. 

Due to Brexit we are temporarily unable to ship to the UK. Shipping to Northern Ireland will remain in place.

Delivery Times
Ireland (ROI & NI) EU (Mainland Only)
2-4 Working Days 4-6 Working Days

Some products have an extended delivery time, this is noted on the products.

Delivery Rates

Country Orders Under €129 Orders Over €129
Ireland (ROI & NI) €7.99 €0.00
Austria €24.99 €17.00
Belgium €21.99 €14.00
Czech Republic €24.99 €17.00
Denmark €24.99 €17.00
Finland €36.99 €29.00
France €21.99 €14.00
Germany €21.99 €14.00
Hungary €28.99 €21.00
Italy €34.99 €23.00
Luxenburg €21.99 €14.00
Netherlands €21.99 €14.00
Poland €21.99 €17.00
Portugal €36.99 €29.00
Slovakia €28.99 €21.00
Slovenia €28.99 €21.00
Spain €34.99 €27.00
Sweden €34.99 €27.00

 

A selection of the products we sell are only licensed for sale within the Republic Of Ireland and can not be shipped outside of the country. These products are noted as only being available within the Republic of Ireland on the individual product pages.

There may be an addition charge on certain bulky items. This charge will be clearly marked on an applicable products and will be explained on the checkout page before payment has been made.

Agridirect Returns Policy

We’re sorry your purchase didn’t work out. But don’t worry; we have a great returns policy to help you out.

All purchases can be returned to us within 14 days of delivery and returned goods must be received within 14 days from the date you informed us of the return.

Purchases may be opened for inspection but must not be used and must be repackaged securely in the original packaging if you wish to return it.

If we discover goods have been used or there has been a loss in value of the goods due to damage to the goods, while in your care or whilst being returned to us, we will reduce the amount refunded, which may amount to the full cost of the product, to cover loss of value of goods.

All returns should be complete which includes boxes, manuals and accessories that may have been included with the order.

All returns must be packaged appropriately for shipping, we will not accept responsibility for damages or loss which occur during shipping of a return product.

We accept no responsibility for goods damaged or lost while in transit to us. 

How do I return a product?

We have partnered with DPD to make your returns process easy and secure. simply follow the steps below and bring your package to an official DPD pickup point.

1) All returns must be accompanied with a fully filled out returns form which can be downloaded here.

2) To print off your return label click here or visit www.dpd.ie/returns and follow the on-screen instructions. Make sure and use your order number as your reference.

  • Select “Continue as Guest”
  • Select “Agridirect” from the drop-down menu
  • Select your reason for returning
  • Select the size of the package you wish to return
  • Accept DPD’s terms and conditions
  • Fill in your payment details
  • Fill in your own details
  • Follow the instructions to print off your label

3) Bring your package to a DPD pickup point. To find your nearest drop off point here.

Once the returned product has been received into our warehouse and been fully inspected a refund will be issued.

If you choose not to use the DPD returns service we recommend that you use a method that can be tracked.

For the return of bulk products please contact us at sales@agridirect.ie

I have received a damaged product from you, what should I do?

First off, if you have received a damaged electrical product from us, do not plug it in. Any electrical products that are plugged in are deemed ‘as used and accepted’ and are not accepted as returns. All damages must be reported to us via phone or email within 24hours of receipt of goods. Please ensure you check your items upon delivery.

How do I begin the returns process?

If you wish to begin the return process, please email us at sales@agridirect.ie and ensure the following information is included in your email. Your name, phone number, Order id, the item you wish to return, reason for return and if the product is damaged we require photos of the product.

Once you have sent us all required information a member of our team will assess your claim and will contact you as soon as possible. Please hold off on returning products until a member of our team has called you to confirm.

Refunds

Once the returned product has been returned to us and fully inspected a refund will be issued.

Please Note: A typical timeline for a refund to show in your account is up to 10 working days from the date processed, depending on your bank.

 

 

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