Volume:
Topimec Pour-on for Cattle 0.5% is used for the treatment and control of gastro-intestinal nemotades, lungworms, warbles, chotioptic and sarcoptic mange mites and sucking and biting lice of beef and non-lactating dairy cattle.
Active Ingredient: Ivermectin
Target Species: Cattle
Treats and Controls: Gastro-intestinal roundworms, lungworms, eyeworms, mites and lice
Administration Method: Pour-on
Withdrawal Time: 28 days for animals intended for meat and offal, Not permitted for use on animals producing milk for human consumption. Do not use in non-lactating dairy cows including pregnant dairy heifers within 60 days prior to calving.
Dosage: 1 ml per 10 kg of bodyweight
Body Weight | Dose Volume | Number of full doses per pack: | ||
1 Litre | 2.5 Litre | 5 Liter | ||
50kg | 5 ml | 200 | 500 | 1000 |
100kg | 10 ml | 100 | 250 | 500 |
150kg | 15 ml | 67 | 167 | 333 |
200kg | 20 ml | 50 | 125 | 250 |
250kg | 25 ml | 40 | 100 | 200 |
300kg | 30 ml | 33 | 83 | 167 |
350kg | 35 ml | 29 | 71 | 143 |
400kg | 40 ml | 25 | 63 | 125 |
450kg | 45 ml | 22 | 56 | 111 |
500kg | 50 ml | 20 | 50 | 100 |
550kg | 55 ml | 18 | 45 | 91 |
600kg | 60 ml | 17 | 41 | 83 |
Always read the label and all enclosed information for Topimec Pour-on before administering to animals!
Signs and effects of infected livestock |
Infection: Gut Worm
Symptoms: Diarrhoea, decreased appetite, loss of weight Effects: Gutworm can cause severe damage to the stomach and small intestine which will cause parasitic gastroenteritis, this will not only negatively affect the health of the animal but will affect the profitability for the farmer. |
Infection: Lungworm Symptoms: Short, sharp cough that becomes worse with exercise, in severe cases the animal will have obvious difficulty breathing. Effects: Lungworm infections cause a high susceptibility to respiratory viruses and bacteria. Infected cattle are prone to contracting severe bronchial pneumonia which if left untreated can lead to death. |
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis.
Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl) avermectin A1a (22,23-dihydroavermectin B1b).
Pharmacodynamics
Ivermectin is a semisynthetic, anthelminitic agent. It is an avermectin, a group of pentacyclic sixteen-membered lactones (i.e., a macrocyclic lactone disaccharide) derived from the soil bacterium Streptomyces avermitilis. Avermectins are potent and broad-spectrum anti-parasitic agents.
Mechanism of action
Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria.
This binding causes an increase in the permeability of the cell membrane to chloride ions and results in hyperpolarization of the cell, leading to paralysis and death of the parasite.
Ivermectin also is believed to act as an agonist of the neurotransmitter gamma-aminobutyric acid (GABA), thereby disrupting GABA-mediated central nervous system (CNS) neurosynaptic transmission.
Ivermectin may also impair normal intrauterine development of O. volvulus microfilariae and may inhibit their release from the uteri of gravid female worms.
Here at Agridirect we have joined forces with DPD to ensure all packages are delivered promptly and safely to you. We ship to all mainland countries within the EU. Deliveries take place Monday to Friday excluding bank holidays. Once your order has been dispatched from our warehouse you will be notified by email. If there is a delay with your order for any reason you will be contacted immediately.
Due to Brexit we are temporarily unable to ship to the UK. Shipping to Northern Ireland will remain in place.
Ireland (ROI & NI) | EU (Mainland Only) |
2-4 Working Days | 4-6 Working Days |
Some products have an extended delivery time, this is noted on the products.
Country | Orders Under €129 | Orders Over €129 |
Ireland (ROI & NI) | €7.99 | €0.00 |
Austria | €24.99 | €17.00 |
Belgium | €36.99 | €29.00 |
Czech Republic | €24.99 | €17.00 |
Denmark | €24.99 | €17.00 |
Finland | €36.99 | €29.00 |
France | €36.99 | €29.00 |
Germany | €36.99 | €29.00 |
Hungary | €28.99 | €21.00 |
Italy | €34.99 | €23.00 |
Luxenburg | €36.99 | €29.00 |
Netherlands | €36.99 | €29.00 |
Poland | €21.99 | €17.00 |
Portugal | €36.99 | €29.00 |
Slovakia | €28.99 | €21.00 |
Slovenia | €28.99 | €21.00 |
Spain | €34.99 | €27.00 |
Sweden | €34.99 | €27.00 |
A selection of the products we sell are only licensed for sale within the Republic Of Ireland and can not be shipped outside of the country. These products are noted as only being available within the Republic of Ireland on the individual product pages.
There may be an addition charge on certain bulky items. This charge will be clearly marked on an applicable products and will be explained on the checkout page before payment has been made.
We’re sorry your purchase didn’t work out. But don’t worry; we have a great returns policy to help you out.
All purchases can be returned to us within 14 days of delivery and returned goods must be received within 14 days from the date you informed us of the return.
Purchases may be opened for inspection but must not be used and must be repackaged securely in the original packaging if you wish to return it.
If we discover goods have been used or there has been a loss in value of the goods due to damage to the goods, while in your care or whilst being returned to us, we will reduce the amount refunded, which may amount to the full cost of the product, to cover loss of value of goods.
All returns should be complete which includes boxes, manuals and accessories that may have been included with the order.
All returns must be packaged appropriately for shipping, we will not accept responsibility for damages or loss which occur during shipping of a return product.
We accept no responsibility for goods damaged or lost while in transit to us.
We have partnered with DPD to make your returns process easy and secure. simply follow the steps below and bring your package to an official DPD pickup point.
1) All returns must be accompanied with a fully filled out returns form which can be downloaded here.
2) To print off your return label click here or visit www.dpd.ie/returns and follow the on-screen instructions. Make sure and use your order number as your reference.
3) Bring your package to a DPD pickup point. To find your nearest drop off point here.
Once the returned product has been received into our warehouse and been fully inspected a refund will be issued.
If you choose not to use the DPD returns service we recommend that you use a method that can be tracked.
For the return of bulk products please contact us at sales@agridirect.ie
First off, if you have received a damaged electrical product from us, do not plug it in. Any electrical products that are plugged in are deemed ‘as used and accepted’ and are not accepted as returns. All damages must be reported to us via phone or email within 24hours of receipt of goods. Please ensure you check your items upon delivery.
How do I begin the returns process?
If you wish to begin the return process, please email us at sales@agridirect.ie and ensure the following information is included in your email. Your name, phone number, Order id, the item you wish to return, reason for return and if the product is damaged we require photos of the product.
Once you have sent us all required information a member of our team will assess your claim and will contact you as soon as possible. Please hold off on returning products until a member of our team has called you to confirm.
Once the returned product has been returned to us and fully inspected a refund will be issued.
Please Note: A typical timeline for a refund to show in your account is up to 10 working days from the date processed, depending on your bank.
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