Cydectin drench for sheep is used for the treatment and control of adult and immature gastro-intestinal roundworms and adult lungworms.

Active Ingredient: Mexidectin Solid

Target Species: Sheep

Administration Method: Oral drench

Treats and Controls: Gastro-intestinal worms, lungworms

Withdrawal Time: 14 days for sheep intended for meat and offal. 5 days for sheep producing milk for human consumption

Dosage for sheep: 1 ml per 5 kg of bodyweight.

Always read the label and all enclosed information for Cydectin Drench for sheep before administering to animals!

Key Features of Cydectin Drench for sheep

• Aids treatment and control of adult and immature gastro-intestinal roundworms and adult lungworms.
• 14 day withdrawal for sheep intended for meat and offal. 
• 5 day withdrawal for sheep producing milk for human consumption
• Oral drench
• Easy application

How sheep contract worms:

This product is only licensed for sale within the Republic of Ireland

Click here to Download Data Sheet

Health Products Regulatory Authority

Summary of Characteristics

1 NAME OF THE VETERINARY MEDICINAL PRODUCT
Cydectin 0.1% w/v oral drench for sheep

2 QUALITATIVE AND QUANTITATIVE COMPOSITION
Each ml contains
Active substance
Moxidectin Solid 1.00 mg

Excipients
Benzyl Alcohol 40.00 mg
Butylated Hydroxy Toluene 2.50 mg
Disodium Edetate 0.27 mg

3 PHARMACEUTICAL FORM
Oral solution

4 CLINICAL PARTICULARS
4.1 Target Species
Sheep

Each ml contains
Active substance
Moxidectin Solid 1.00 mg

Excipients
Benzyl Alcohol 40.00 mg
Butylated Hydroxy Toluene 2.50 mg
Disodium Edetate 0.27 mg

4.2 Indications for use, specifying the target species
Infections of sheep with parasites sensitive to moxidectin.
For the treatment and prevention of infections caused by:

Adult and immature gastro-intestinal nematodes:
- Haemonchus contortus (including inhibited larvae)
- Ostertagia circumcincta (including inhibited larvae)
- Ostertagia trifurcata
- Trichostrongylus axei (including inhibited larvae)
- Trichostrongylus colubriformis
- Trichostrongylus vitrinus
- Nematodirus battus
- Nematodirus spathiger
- Nematodirus filicolis (adults only)
- Strongyloides papillosus (larval stages only)
- Cooperia curticei (adults only)
- Cooperia oncoaphora
- Oesophagostomum columbianum
- Oesophagostomum venulosym (adults only)
- Chabertia ovina
- Trichuris ovis (adults only)

Adult respiratory tract nematode:
- Dictyocaulus filaria

The product has a persistent effect in preventing reinfection:
• for 5 weeks by Ostertagia circumcincta and Haemonchus contortus
• for 4 weeks by Oesophagostomum columbianum

Clinical trials, after experimental and natural infection, have shown that the product is effective against certain benzimidazole resistant strains of:
• Haemonchus contortus
• Ostertagia circumcincta
• Trichostrongylus colubriformi
Cooperia curticei

4.3 Contraindications
None

4.4 Special warnings for each target species
None

4.5 Special precautions for use
None known

4.6 Adverse reactions (frequency and seriousness)
None known

4.7 Use during pregnancy, lactation or lay
Moxidectin has been shown to be safe for use in pregnant, lactating and breeding animals.

4.8 Interaction with other medicinal products and other forms of interaction
None known

4.9 Amounts to be administered and administration route
Should be given as a single oral drench of 1 ml/5 kg live bodyweight, equivalent to 200 μg moxidectin/kg live bodyweight, using any standard drenching equipment.

4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
Symptoms generally do not occur at less than 5 times the recommended dose.
They are manifested as transient salivation, depression, drowsiness and ataxia 8 to 12 hours post-treatment. Treatment is not generally necessary and recovery is generally complete within 24 to 48 hours.
There is no specific antidote.

4.11Withdrawal Period(s)
Meat and offal: 14 days.
Milk: 5 days

5 PHARMACOLOGICAL or IMMUNOLOGICAL PROPERTIES
Pharmacotherapeutic group:
Endectocides (milbemycins)

ATC Vet code:
QP 54 AB 02
 

5.1 Pharmacodynamic properties
Moxidectin is a parasiticide active against a wide range of economically important internal and external parasites and is a second generation macrocyclic lactone of the milbemycin family. Its principal mode of action is interfering with neuromuscular transmission of the GABA (gamma amino butyric acid)-gated or glutamate-gated chloride channels.
Moxidectin stimulates the release of GABA and increases its binding to the postsynaptic receptors.
The net effect is to open the chloride channels on the postsynaptic junction to allow the inflow of chloride ions and induce an irreversible resting state.
This results in flaccid paralysis and eventual death of parasites exposed to the drug.

5.2 Pharmacokinetic properties
22% of an oral dose of moxidectin is absorbed with maximum blood concentrations being achieved 9 hours post treatment.
The drug is distributed throughout the body tissues but due to its lipophilicity the target tissue is fat where concentrations are 10 to 20 times higher than those found in other tissues.
The depletion half life in fat is 23-28 days.
Moxidectin undergoes limited biotransformation by hydroxylation.
The only significant route of excretion is the faeces.

6 PHARMACEUTICAL PARTICULARS
6.1 List of excipients
Benzyl Alcohol
Butylated Hydroxytoluene
Disodium Edetate
Polysorbate 80
Propylene Glycol
Dibasic Sodium Phosphate Dodecahydrate
Monobasic Sodium Phosphate Dihydrate
Purified Water

6.2 Incompatibilities
Not to be mixed with other Veterinary Medicinal Products before administration.

6.3 Shelf-life
24 months
Once opened use the product within 6 months.

6.4 Special precautions for storage
Protect from light.
Do not store above 25°C

6.5 Nature and composition of immediate packaging
Polyethylene containers of 1 litre, 2.5 litre and 5 litre content.

6.6 Special precautions for the disposal of unused veterinary medicinal products or waste materials
DANGEROUS to fish and aquatic life.
Do not contaminate ponds, waterways or ditches with the product or used containers.
Any unused product or waste material should be disposed of in accordance with national requirements.

7 MARKETING AUTHORISATION HOLDER
Fort Dodge Animal Health Limited,
Flanders Road,
Hedge End,
Southampton,
SO30 4QH,
United Kingdom.

8 MARKETING AUTHORISATION NUMBER(S)
VPA 10861/044/001

9 DATE OF THE FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION
11th October 2005

10 DATE OF REVISION OF THE TEXT
12th February 2009
 

Drench correctly
Sheep Oral Drench
The drenching technique is a vital part of ensuring that the wormer does its job effectively.
Make sure the sheep are properly restrained and cannot leap around when they are being drenched so they swallow the whole amount.
Sheep can also suffer serious injury, or even death, if they are unrestrained and the gun penetrates the tissues at the back of the mouth.
Place a hand under the head and tilt slightly to the side.
Slot the nozzle in the gap between molar and incisor teeth and then over the back of the tongue.
If the wormer is just put into the mouth, it will bypass the rumen as it escapes down the oesophageal groove and will be less effective.
This is particularly important for white (BZ) drenches.

Dosing Weigh – do not guess Underestimating the weight of sheep is a common cause of underdosing. Select and weigh the biggest sheep in the group to determine the correct dose. If there is a wide range of weights, consider splitting the group, then weigh the heaviest in each section. Do not forget to check that the weigh crate is accurate before starting!

Calibrate and maintain the drench gun
Always check the gun is delivering the right amount before you drench. Remove the plunger from a 10 ml syringe, put a thumb over the end and squirt the dose into it, making sure there are no air bubbles left. Adjust the gun until the dose delivered is correct. Drenching guns should also be well maintained and replaced regularly. Clean with warm soapy water after use and check springs and tubes to make sure there are no kinks that will form air bubbles.

Withholding food
Research has shown that the efficacy of the white (BZ) and clear (AV) drenches can be improved by withholding food for 12–24 hours before treatment. It is not advised to deprive heavily pregnant ewes of food, so if you treat this class of stock with anthelmintics, you may wish to use yellow drenches (LV) because their efficacy is less dependent on rumen fill.

Storage
Wormers should be stored securely, away from direct sunlight at 4–25°C. Check the use-by date and, once open, use within the time shown on the packaging. Shake white (BZ) products well before use.

Delivery Information

Delivery Service

Here at Agridirect we have joined forces with DPD to ensure all packages are delivered promptly and safely to you. We ship to all mainland countries within the EU. Deliveries take place Monday to Friday excluding bank holidays. Once your order has been dispatched from our warehouse you will be notified by email. If there is a delay with your order for any reason you will be contacted immediately. 

Due to Brexit we are temporarily unable to ship to the UK. Shipping to Northern Ireland will remain in place.

Delivery Times

Some products have an extended delivery time, this is noted on the products.

Delivery Rates

A selection of the products we sell are only licensed for sale within the Republic Of Ireland and can not be shipped outside of the country. These products are noted as only being available within the Republic of Ireland on the individual product pages.

There may be an addition charge on certain bulky items. This charge will be clearly marked on an applicable products and will be explained on the checkout page before payment has been made.

Agridirect Returns Policy

We’re sorry your purchase didn’t work out. But don’t worry; we have a great returns policy to help you out.

All purchases can be returned to us within 14 days of delivery and returned goods must be received within 14 days from the date you informed us of the return.

Purchases may be opened for inspection but must not be used and must be repackaged securely in the original packaging if you wish to return it.

If we discover goods have been used or there has been a loss in value of the goods due to damage to the goods, while in your care or whilst being returned to us, we will reduce the amount refunded, which may amount to the full cost of the product, to cover loss of value of goods.

All returns should be complete which includes boxes, manuals and accessories that may have been included with the order.

All returns must be packaged appropriately for shipping, we will not accept responsibility for damages or loss which occur during shipping of a return product.

We accept no responsibility for goods damaged or lost while in transit to us. 

How do I return a product?

We have partnered with DPD to make your returns process easy and secure. simply follow the steps below and bring your package to an official DPD pickup point.

1) All returns must be accompanied with a fully filled out returns form which can be downloaded here.

2) To print off your return label click here or visit www.dpd.ie/returns and follow the on-screen instructions. Make sure and use your order number as your reference.

• Select “Continue as Guest”
• Select “Agridirect” from the drop-down menu
• Select your reason for returning
• Select the size of the package you wish to return
• Accept DPD’s terms and conditions
• Fill in your payment details
• Fill in your own details
• Follow the instructions to print off your label

3) Bring your package to a DPD pickup point. To find your nearest drop off point here.

Once the returned product has been received into our warehouse and been fully inspected a refund will be issued.

If you choose not to use the DPD returns service we recommend that you use a method that can be tracked.

For the return of bulk products please contact us at sales@agridirect.ie

I have received a damaged product from you, what should I do?

First off, if you have received a damaged electrical product from us, do not plug it in. Any electrical products that are plugged in are deemed ‘as used and accepted’ and are not accepted as returns. All damages must be reported to us via phone or email within 24hours of receipt of goods. Please ensure you check your items upon delivery.

How do I begin the returns process?

If you wish to begin the return process, please email us at sales@agridirect.ie and ensure the following information is included in your email. Your name, phone number, Order id, the item you wish to return, reason for return and if the product is damaged we require photos of the product.

Once you have sent us all required information a member of our team will assess your claim and will contact you as soon as possible. Please hold off on returning products until a member of our team has called you to confirm.

Refunds

Once the returned product has been returned to us and fully inspected a refund will be issued.

Please Note: A typical timeline for a refund to show in your account is up to 10 working days from the date processed, depending on your bank.